Vol 24, No 2 (2020)

Articles
CHATBOTS AS INNOVATIONS OF DIGITAL MEDICINE. NEW PROSPECTS OF THE RESEARCH DURING virus COVID-19 PANDEMIC
Mantskava M.M.

Abstract

During the virus CoViD-19 pandemic, people at risk deserve special attention. One of the reasons that risk factors form is a violation of adequate blood circulation. Evaluation of microcirculation resistance by studying the effectiveness of the functional state of resistive vessels is one of the key issues of blood circulation, which plays a very important role at arterial hypertension, diabetes mellitus, Raynaud's phenomenon. In this article, we had discussed the new approaches to the construction of chatbot systems, also we had presented some pilot results about their testing. In situation today, during the period of social restrictions and recommendations on physical distance in the period of the quarantine, people, in need of prevention especially, must have constant control in home. It's very especially important. This can be done with the simplest chatbot systems that are described in the article.
Russian Journal of Biomechanics. 2020;24(2):126-132
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BRAIN BIOMECHANICS: MONITORING THE BIOMECHANICAL PROPERTIES OF THE HUMAN CRANIOSPINAL SYSTEM
Atiskov Y.A., Akshulakov S.K., Belkin A.A., Nazaralieva E.T., Riznich V.P., Safin S.M., Safin I.S., Gaydar B.V., Khachatryan W.A.

Abstract

The existing methods of assessing the biomechanical properties of the human craniospinal system are reduced to the study of the dynamics of changes in intracranial pressure with a dosed increase in intracranial volume by introducing a certain volume of fluid into the cranial space. These studies are discrete, traumatic. In different neurosurgical clinics, retrospective analysis of 1732 studies of biomechanical properties of the human craniospinal system (compliance, pressure-volume ratio, elasticity) in the period 1988-2014 were conducted. In order to establish a diagnosis or clarify the tactics of surgical treatment, a relationship between the amplitude of the intracranial pressure oscillation at the pulse rate, intracranial pressure and the compliance of the craniospinal system was established. In a single classical test with the introduction of a bolus of a small volume of fluid, and the indicators of biomechanical properties of the human craniospinal system are numerically evaluated. It is assumed that between two pulse waves (in the second range), these indicators do not change significantly, that is, in fact, we are talking about monitoring biomechanical properties of the human craniospinal system. A mathematical model is proposed that formalizes the relationship between biomechanical properties of the human craniospinal system and the dynamics of intracranial pressure oscillations at the pulse rate. Comparison of the results of the assessment of the main biomechanical indicators by the classical method and the proposed method established their high correlation. On the basis of this, an algorithm is proposed that can be used to create the original biomechanical properties of the human craniospinal system and intracranial pressure monitor.
Russian Journal of Biomechanics. 2020;24(2):133-147
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CLINICO-PHYSIOLOGICAL FOUNDATION OF APPLICATION OF EXOSKELETON “EXOATLET” DURING WALKING OF PATIENTS WITH DISSEMINATED SCLEROSIS
Kotov S.V., Petrushanskaya K.A., Lizhdvoj V.J., Pismennaya E.V., Sekirin A.B., Sutchenkov I.A.

Abstract

On the basis of investigations of the biomechanical and innervative structure of walking of patients with disseminated sclerosis, authors of this article gave foundation of application of the exoskeleton ExoAtlet in this disease. Earlier, these authors revealed that patients with disseminated sclerosis have some similar disorders, which are characteristic of all patients with diseases of the locomotor system, namely, reduction of walking, velocity, weakening of the support and push functions of the lower extremities, pronounced decrease of maxima of electrical activity of muscles during the locomotor cycle. On the example of the concrete patient, authors established that this patient has the specific peculiarities of walking, characteristic only of this disease. Authors consider that the following peculiarities of walking are specific only to patients with disseminated sclerosis: cyclic character of the vertical component of the ground reaction force Rz and electromiography-pattern of muscles, unsteadiness of gait, triangular or trapezoid shape of the vertical component Rz of the ground reaction force, equinus of the foot and the ankle joint often in combination with recurvation at the knee joint, considerable diminution of the main flexion at the knee joint in one or both lower extremities, reduction of electrical activity of muscles and its prolongation for most part of the stance phase. With the purpose of investigations of the energetic parameters of walking and revealing the resonance properties of the lower extremities in this disease, authors studied electromiography-pattern of two symmetrical muscles of the lower extremities (both mm. rectus femoris and both mm. biceps femoris) during walking at different cadences in this patient. Method of training of walking in the exoskeleton for patient with disseminated sclerosis included the total time of training, time of walking without rest, distance, which patient could walk for the session, walking velocity, cadence and double step length during walking in the exoskeleton, total number of steps for the session. Authors ascertained that considerable improvement of the biomechanical and innervative structure of walking takes place after the course of training in the exoskeleton ExoAtlet in combination with the medicines, changing the course of the disseminated sclerosis, which is revealed in increase of walking velocity, in growth of the amplitude of the angular displacements at the joints of the lower extremities, in disappearance of phenomena of cyclicity of electromiography-pattern, in change of the form of the vertical component Rz of the ground reaction force from the triangular or trapezoid to the clear-cut two-peaked in parallel with increase of the extreme values of Rz curve, in growth of the maximums of activity of all muscles and their concentration in the adequate phase of the locomotor cycle, in rise of the mean electrical activity (muscle capacity) with increase of walking velocity, in appearance of two parabola branches with presence of the distinct minimum in the curve of the summary integral for distance of 10 meters.
Russian Journal of Biomechanics. 2020;24(2):148-166
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THE PROBLEM OF CREATING A FOLDED CONFIGURATION INFLATION BALLOON OF THE CORONARY STENT DELIVERY SYSTEM
Nushtaev D.V., Volkov-Bogorodsky D.B., Ardatov K.V.

Abstract

A new numerical-analytical method was developed for constructing a folded configuration of an inflation balloon using Archimedes spirals as functions that approximate the cross-sectional profile. The proposed method is implemented in a console application for Windows, which allows in the shortest possible time to create models of cylinders of various sizes and types of installation. The efficiency of the created algorithm is shown by the example of solving two test problems. A good correlation of the simulation results with experimental data was obtained. The construction of the folded inflation balloon configurations was carried out on the basis of the created program module.
Russian Journal of Biomechanics. 2020;24(2):167-176
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CALCULATION AND VISUALIZATION of THE ENAMEL AND DENTIN MATRIX OF ELASTIC PARAMETERS
Muslov S.A., Zaitseva N.V., Astashina N.B., Arutyunov S.D., Nikitin V.N.

Abstract

The capabilities of the ELATE and MATLAB packages for visualization of the elastic properties of hard tooth tissues are demonstrated. A visual confirmation of the fact of the elastic anisotropy of the hard tissues of the tooth due to the crystal structure of their mineral component was obtained. The study of the indices of anisotropy of enamel and dentin as an inhomogeneous anisotropic medium becomes of practical importance when studying the problems of the strength of tooth tissues and the quality of restorations.
Russian Journal of Biomechanics. 2020;24(2):177-186
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ANALYSIS OF IMPEDANCE CHARACTERISTICS OF THE RESPIRATORY SYSTEMs OF ANIMALS AND HUMAN
Dragan S.P., Bogomolov A.V., Kezik V.I.

Abstract

The aim of the study was to modify the method of pulsed oscillometry of the respiratory system of biological objects in the interests of the possibility of its application to extrapolate the medical and biological effects of extreme physical factors of the conditions of professional activity from animals to humans. The method is based on a verified algorithm for determining the impedance characteristics of the human lungs (resonant frequency, active and reactive frequency-dependent components of the impedance) using a two-microphone technique. The impedance characteristics of the respiratory system of animals (30 rats, 15 rabbits, and 15 sheep) in the frequency range from 5 to 100 Hz were measured on decapitated animals when the trachea was connected to an experimental setup including a loudspeaker, waveguide, two measuring microphones, an impedance wall, and a connecting tube designed to connect the installation to the trachea. The impedance characteristics of the respiratory system in humans (40 athletes aged 20-30 years) in the same frequency range were measured during free breathing: a standard mouthpiece was installed as a perforated panel at the end of the waveguide. As a result of the experiment, the resonance frequency of the respiratory system, the absorption coefficient of acoustic vibrations, the resistance at the resonance frequency and the acoustic quality factor of the respiratory system were determined. The results of theoretical and experimental studies indicate that the resonant frequencies of the respiratory system in humans, rabbits and sheep are close to each other, and the resonant frequencies of the respiratory system of rats and humans are significantly different. This allows the use of rabbits and sheep as an adequate biological model for extrapolating the effects of extreme factors from animals on humans in terms of the state of the respiratory system. Extrapolation of similar results from rats to humans should be carried out taking into account the ratio of the impedance characteristics of the respiratory systems.
Russian Journal of Biomechanics. 2020;24(2):187-195
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ASSESSMENT OF BIOMECHANICAL DISORDERS OF THE SHOULDER JOINT IN PATIENTS WITH CERVICAL-SHOULDER SYNDROME AFTER INJURIES TO THE UPPER ARM
Kalinsky E.B., Chernyaev A.V., Slinyakov L.Y., Bogatov V.B., Goncharuk Y.R., Chekanov A.S., Kolyshenkova V.A., Eremushkin M.A.

Abstract

The consequences of injuries and diseases of the shoulder joint can be either isolated or combined with pathology of the cervical spine. The polymorphism of the pathology significantly complicates the task of rehabilitation of such patients. The authors analyzed biomechanical disorders in the shoulder joint in cervical-brachial syndrome with three main types of injuries: articular, vertebrogenic, and mixed myofascial type. It was shown that the greatest difficulty in terms of violation of biomechanics and subsequent rehabilitation is represented by the articular variant, i.e. in patients who have suffered an injury to the capsular ligamentous apparatus of the shoulder joint.
Russian Journal of Biomechanics. 2020;24(2):196-202
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EFFECTS OF CEMENT THICKNESS JOINT OF THE TRANSDENTAL IMPLANT WITH THE TOOTH TISSUE ON ITS ADHESION PROPERTIES. NUMERICAL-EXPERIMENTAL STUDY
Dzhalalova M.V., Stepanov A.G.

Abstract

In previous experimental investigations, adhesion strength was studied with a static tensile load of dental cement joints of an individual milled transdental implant with hard tissues of the tooth root. At the second stage, the effect of artificially formed roughness of the implant surface on the adhesive properties of the cement joint implant-tooth was studied. The implants were sandblasted with alumina pellets of sizes 50, 150, 250 microns - the artificial roughness was the best when processed with granules of 250 microns. In the present work, the next stage of research is presented - the effect of the thickness of the cement joint “transdental implant - cement - dentin tooth” on its adhesive properties. Before milling samples of transdental implants on a digital model, the intra-root part of the implant was reduced by 20, 50, and 100 μm, sandblasted with alumina powder of 250 μm grain and fixed to a removed tooth on cements that have worked best in previous studies. All tests were carried out on an Instron 5900 experimental setup. Zirconia implants were considered in combination with the two most effective cements Fuji -1 and Multilink-N (with the highest adhesion-strength characteristics). As a result of experiments, the combination of zirconia material with Fuji -1 cement turned out to be much better than with Multilink-N cement. A computer simulation of the process of drawing a prototype of a zirconium implant from a tooth root sample with different thicknesses of cement film: 20, 50 and 100 μm was carried out. A satisfactory qualitative and quantitative agreement was obtained between the results of three-dimensional numerical analysis and experiment: with a decrease in the thickness of the cement film from 100 to 20 μm, an improvement in the properties of the adhesive compound is observed, and a thickness of 50 μm can be considered optimal.
Russian Journal of Biomechanics. 2020;24(2):203-215
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BIOMECHANICAL MECHANISMS OF ACTION OF LOW-FREQUENCY ACOUSTIC VIBRATIONS ON A PERSON
Ivanov N.I., Zinkin V.N., Slivina L.P.

Abstract

The aim of this work to substantiate the mechanisms of action of low-frequency acoustic vibrations on humans, caused by mechanical interaction of acoustic oscillations with the anatomical structures of the body. One of the modern features of industrial noise is the domination noise spectrum of the low frequency noise and infrasound with high intensity. To characterize these ranges, the scientific literature uses the term low-frequency acoustic oscillations, due to similar physical properties and biological effects on the human body and animals. It is proven that infrasound has negative effects on many organs (respiratory, hearing, vision, etc.) and human systems (central and autonomic nervous, etc.) and leads to the development of diseases, including professional (sensorineural hearing loss, vestibulopathy, autonomic disorders). On this basis, infrasound is included in the list of harmful production factors. A number of biological effects is formed by a direct mechanical interaction of acoustic oscillations with the anatomical structures of the human body. The length of the acoustic wave and its intensity are decisive parameters for the formation of a reaction in the human body. The interaction of low frequency acoustic oscillations with the anatomical structures of the body must be considered as the interaction of two mechanical systems that leads to the development of various physical effects in tissues and organs (diffraction, resonance, elastic waves, cavitation, etc.). The latter are the basis of the direct action of acoustic oscillations and lead to anatomical damage of the tissues, a conformational disturbance of cellular structures and macromolecules, activation of receptors (mechano-, proprio, vestibuloadaptive, etc.). Biomechanical effect of low-frequency acoustic oscillations should be taken into account in the normalization of low frequency sound range, and determining ways and means of protection from low-frequency acoustic oscillations not only the organ of hearing and the head and internal organs.
Russian Journal of Biomechanics. 2020;24(2):216-231
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ANTHROPOMORPHIC MECHATRONICS FOR SPORTS AND MEDICINE
Medvedev V.G.

Abstract

The article describes the prospects for the development and implementation of anthropomorphic mechatronics to the practice of sports and medicine. The main objects of research were sport and medical exoskeletons. The main function of a sport exoskeleton is to get the best conditions for the formation and increasing of the effectiveness of sport technique. The technology offers a completely new approach to the transfer of "sports" knowledge and skills. Usually, the coach affects on audiovisual channels, but a sport exoskeleton transmits a significant amount of information through proprioceptive channels (sensations) when performing a real exercise, and not only ideomotor one. Thus, control of the athlete's body segments is carried out independently on the basis of the received signals from his body, and not only because feedback from the coach. This is the main effect for athlete, due to which it is possible to significantly increase the quickness of transmission of training information and, as a consequence, the quickness of mastering of effective sport technique. The using of exoskeletons in rehabilitee medicine is primarily need for a comprehensive solution in the rehabilitation of patients with impaired or loss of motor function due to diseases of various etiologies. In this case, the exoskeleton acts as a mechanism that determines the body segment movement. Management of such an exoskeleton is carried out through a special interface "brain-computer". The task of training medical personnel using robotic complexes generally coincides with the sports tasks associated with the formation of a stable motor skill and the improvement of the technique of movement action. The medical exoskeleton is used as a simulator for the training the structure and the needed characteristics of the movement at performing the operations.
Russian Journal of Biomechanics. 2020;24(2):232-242
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THE ORIGINS OF THE EASTERN MERIDIAN SYSTEM
Yavelov I.S., Dosko S.I., Zholobov A.V., Rochagov A.V., Yavelov O.I.

Abstract

There is no doubt that the mechanical effect on the so-called bioactive points and areas may be extremely useful and leads sometimes to a complete cure for various ailments. The existence and benefits of a reflex therapy are absolutely indisputable. Indeed, from ancient times to the present, the unique experience and empirical knowledge about the meridians connecting the points of influence and the skin with all body systems have been accumulated in the depths of Eastern medicine. Until now, the physical nature of the meridians is unknown and has not been explained by anyone, that’s why the reflex therapy stands apart from standard medicine and is practiced as a semi-legal occupation, despite its obvious benefits and effectiveness. In this paper, an attempt was made to reveal the physical nature of the meridians and, thereby, legalize this ancient and extremely necessary discipline. The authors propose a coherent hypothesis, the main idea of which is the statement that if there is even a slightest wound, the nervous system will immediately send the impulse to increase the blood supply to this spot, in other words, a special address appears, the fresh blood directs that way and causes the healing. The mechanism of redistribution of blood flow is that there is a certain low-frequency modulation of the heart rate, which leads to a local increase in blood flow, as impact zones are characterized by certain reductions in time with the modulations. The corresponding organ in the body also has a similar address (i.e. a certain frequency), and therefore an intensified blood flow rushes there too, providing a vital effect on this organ. As a result, the supported organ more effectively fights the disease. This, in short, is the mechanism of recovery that nature has in place in the presence of heart rhythm modulations that can be made manageable. Naturally, by saturating the blood with exposure agents, we will obtain an increase in their effectiveness due to local penetration directly into the painful area.
Russian Journal of Biomechanics. 2020;24(2):243-247
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DESTRUCTION SIMULATION FOR THE INHOMOGENEOUS BODY BY FINITE ELEMENT METHOD USING COMPUTED TOMOGRAPHY DATA
Bolshakov P.V., Sachenkov O.A.

Abstract

The work is devoted to modelling the bone organ destruction using the finite-element method and taking into account the CT data. In order to evaluate the model, the simulation results for the femur are presented. Such an approach allows to individualize the simulation of the organ and determines the relevance of the study. Numerical studies using the finite element method were performed, an eight-node finite element with linear approximation was used. A linear formulation for an inhomogeneous elastic body was considered. Young’s modulus and ultimate stress were determined using power functions. The dependence of mechanical properties on the optical density was assumed, which, in turn, was determined by linear relationships depending on the Hounsfield numbers. For discretization by the finite element method, the distribution of the mechanical properties of the material for each element was performed according to tomography data. After solving, the stress-strain state problem safety factor was calculated in each node. Based on the calculated safety factor, a decision is made either to thicken the mesh or to remove the finite element. The paper presents the results of calculations using the method for two problems: an inhomogeneous sample and specimen with averaged mechanical properties. The numerical results in these problems illustrate the significant differences in the results of the stress-strain state of the organ and allow us to judge the nature of the destruction of the organ.
Russian Journal of Biomechanics. 2020;24(2):248-258
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